Producers and sellers of electronic cigarettes are urged to shut down websites and other online portals, as well as suspend related advertising.
E-commerce platforms are also required to remove retailers selling e-cigarettes and pull their merchandise, according to a statement released by the State Tobacco Monopoly Administration and the State Administration for Market Regulation.
The ban takes effect immediately.
It is believed that electronic cigarettes have lured minors into regular nicotine use.
According to the State Tobacco Monopoly Administration, research has shown that vaping businesses tend to target young people with their advertising campaigns.
They mislead potential consumers by falsely claiming that their products are harmless and effective for quitting tobacco use, and associate vaping with a fashionable and trendy lifestyle, the administration said in a release explaining the ban.
"A quick search of online shopping platforms returns many results for electronic cigarettes, and some retailers boast total sales of hundreds of thousands of packages," said Wang Ke'an, a researcher with the Chinese Center for Disease Control and Prevention.
"Traditional tobacco products are banned from online sales, and electronic types should be treated equally," he said.
"There are at least 15,000 types of additives that can be put in e-cigarettes to create a range of flavors from mint to tropical fruits," said Sun Jiani, an officer with the WHO China Representative Office.
"While research into the impact of these additives on health is underway, it is proved that e-cigarettes also contain nicotine that can harm the development of children and teenagers."
The move comes just two weeks before one the world's busiest online shopping days, Singles Day, a holiday invented by the Chinese e-commerce website Alibaba.
Some companies like Juul, one of the best known e-cigarettes companies, faces multiple state and federal investigations in the United States, it has targeted the overseas market for e-cigarettes, a strategy its new chief executive, K.C. Crosthwaite, highlighted to employees in an all-hands meeting in September. But that plan has hit roadblocks in Asia, with China's crackdown and India's announcement in September that it would ban the sale of e-cigarettes.
The Chinese government notice also called for stepping up supervision over the entire industry of e-cigarettes, including the brick-and-mortar stores.
There are over 300 million smokers in China, and 28.1 percent of people aged 15 years and older smoke. The country aims at slashing the percentage to 20 percent by 2030.