2021-11-24 16:58


2 Chinese anti-COVID-19 drug candidates enter human trials


Two Chinese antiviral medicine for COVID-19 mainly developed by the Shanghai Institute of Materia Medica under the Chinese Academy of Sciences (CAS) have commenced human trials overseas.

One candidate, coded VV116, is an oral anti-COVID-19 nucleoside drug that has yielded promising results in animal models. It has shown significant inhibiting activity against COVID-19 original strain and variant strain, such as the Delta variant, in vitro tests, the institute said Wednesday.

"VV116 was first approved for clinical trials in Uzbekistan," said Shen Jingshan, a researcher with the institute, adding that human trials are also underway in China.

The other candidate is called FB2001. It is a novel compound designed and synthesized based on the coronavirus' main protease, a key enzyme that plays a pivotal role in viral replication.

Preclinical research also showed that the compound exhibited potent inhibitory activity against the virus in cell culture, said lead researcher Liu Hong.

Researchers conducted phase-1 trials in the United States in March after preclinical research results were published in the journal Science in June 2020.


Gabriel & Co. fine jewelry

  • Farmer's $203000 hom-AD A popular TV show in China on home renovations that has run for seven years, featuring renowned designers, recently came under fire on Chinese social media with netizens slamming the makeover of an earth house in a village as "the wors
  • China Has Lowest Amount of ESource: OT-Team(S,J), National Bureau of Statistics After the data of Chinas 7th National population census got released in May, we could see a significant change on the number of foreigners living in China. It increased from 593,832 in 20
  • Dormitory Collapse In East CSource:Global Times Four people died as a dormitory building partially collapsed on Monday evening in Ganjiang new area, East China's Jiangxi Province. The cause of the collapse is under investigation. At 6:45 pm on Monday, the dormitory b
  • 20211124 China NewsClick the blue words above to follow our Wechat. 202111.24 Voice Broadcast 3 minutesKnow China 0 1 Xuzhou Construction Machinery Group debuted five new all-terrain cranes on Tuesday, marking a milestone in the domestic production of high-e
  • Suzie C Revamped Lane House BySophie Steiner The Place Powerhouse restaurateur and wine aficionado Li Ze (Ottimo,SOiF,theWarehouse) is at again, with the recent launch of yet another modern French bistro C Suzie C next to the Capella Complex . The revamped lane house

Subscribe by Email

Follow Updates Articles from This Blog via Email

No Comments